Leeds In Vitro Diagnostics Co-operative

Professor Phil Quirke

Multidisciplinary Pathology Theme Lead

Phil Quirke has an active research group in bowel cancer as well as being the Academic Training Programme Director for West Yorkshire, the Chair of the NHS Bowel Cancer Screening Programme Pathology Committee and President of the Pathological society of Great Britain and Ireland.

His major interests are in bowel cancer. The first YCR programme concentrates on (i) quality of surgery and multidisciplinary treatment (ii) response to therapy in clinical trials in colorectal cancer contributing to the pathology and molecular pathology assessments (iii) screening and the development of early neoplastic lesions. The second YCR programme is directed at improving outcomes in colorectal cancer in Yorkshire and the Humber. The CRUK programme lead by Professor John Ladbury is aimed at understanding cancer of non-genetic origin and the CRUK programme of Professor Eva Morris into linkage of routine datasets in coloreactal neoplasia.

Professor Quirke is part of the digital pathology group lead by Dr Darren Treanor in collaboration with computing within the University of Leeds with interests in 3 Dimensional histopathology and genotype – phenotype integration. The group is using molecular testing to choose targeted therapies in the MRC Focus 4 trial and are part of the national MRC SCORT network trying to discover new molecular markers. The group is involved in over 30 lower GI cancer trials. Researchers are exploring the value of new forms of microscopy the light sheet microscope and nanoscopy in bowel cancer. The group ollaborates with international colleagues in the Karolinska Hospital, Stockholm, University of Erlangen, University of Aarhus, Denmark, Tokyo University, Cancer Hospital Chennai India, Italian Hospital Buenos aries, Santiago, Chile and Vietnam.

Professor Quirke is an Honorary Fellow of the American College of Colon and Rectal Surgeons, the Association of Coloproctology of Great Britain and Ireland, the Royal College of Surgeons Edinburgh (ad hominem), the Sociedad de Coloproctologica, North West Argentina, the Societad de Coloproctologica Chile, the Russian Society of Colorectal Surgeons and have received the McKeown and Miles medals.

He chairs the NHS Bowel Cancer Screening Pathology Programme and undertake pathology screening research. I am currently the president of the pathological society, an NIHR Senior Investigator and a Fellow of the Academy of Medical Science.